Innate Immunity

Inflammasomes & TLR Signalling

Introduction

Epigenetics includes all the heritable changes other than DNA sequence modificationwitch are involved in the regulation of genic expression. in fact, lots of chemical reaction produced in the genome, like DNA methylation or histones modifications, are able to switch on or off genes expression.

Rapid progress in this research area is driven by the develepoment of good and specific antibodies which are the key tools to elucidate the roles of epigenetic modifications in many diseases.