Caspase-9 (I20) antibody

Caspase-9, CASP-9
Apoptotic protease Mch-6
Apoptotic protease-activating factor 3, APAF-3
ICE-like apoptotic protease 6, ICE-LAP6
Gene name: CASP9, MCH6
As low as $400.00
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00097776
Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3, a protease responsible for proteolytic cleavage of many key proteins involved in apoptosis. Caspase-9 plays a central role in cell death induced by a wide variety of apoptosis inducers including TNFa , TRAIL, anti-CD95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues.
More Information
ID Covalab pab60070
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Peptide corresponding to aa 299- 318 of human caspase-9
Activity cross reaction Reacts with full lengh human Caspase-9.
Species Hu
Labelling None
Form Purified
Preservative NaN3 0.02%
Storage instructions Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Target Caspase-9
Uniprot ID P55211
Gene ID 842
Applications ICC, IF, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
ICC (2 µg/ml)
WB (1 µg/ml)
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