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CD49e antibody (SAM1)
Integrin alpha-5
CD49 antigen-like family member E
Fibronectin receptor subunit alpha
Integrin alpha-F
VLA-5
Gene name: CD49e
CD49 antigen-like family member E
Fibronectin receptor subunit alpha
Integrin alpha-F
VLA-5
Gene name: CD49e
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00122151
CD49e (VLA5 alpha) is a type I transmembrane glycoprotein of the integrin alpha subclass (intergrin 5 alpha), expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells. It binds to RGD sequence in fibronectin and to neural adhesion molecule L1. CD49e interactions are important for maintaining the integrity of the endothelial monolayer, as well as it is involved in monocyte migration, T cell costimulation, regulation of cell survival, and other.
ID Covalab | mab21341 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | SAM1 |
Isotype | IgG2 beta |
Raised in | Mouse |
Immunogen | U937 cells |
Activity cross reaction | Non-human primates, Human |
Species | Hu |
Labelling | None |
Form | Purified |
Preservative | NaN3 15 mM |
Storage instructions | Store at 2-8°C. Do not freeze. |
Target | CD49e |
Uniprot ID | P08648 |
Gene ID | ITGA5 |
Applications | FC |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : FC (1-4 µg/ml) |
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