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C5aR2 antibody (1D9-M12)
C5a anaphylatoxin chemotactic receptor 2
Complement component 5a receptor 2
G-protein coupled receptor 77
Gene name: C5AR2, C5L2, GPR77
Complement component 5a receptor 2
G-protein coupled receptor 77
Gene name: C5AR2, C5L2, GPR77
As low as
$427.30
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00118973
C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.
ID Covalab | mab21319 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | 1D9-M12 |
Isotype | IgG2a kappa |
Raised in | Mouse |
Immunogen | The mouse monoclonal antibody 1D9-M12 recognizes an extracellular epitope on C5aR2 (C5L2), a C5a complement receptor, which is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages. |
Activity cross reaction | L1.2 cells transfected with human C5aR2 |
Species | Hu |
Labelling | None |
Form | Purified (protein A) |
Preservative | NaN3 15 mM |
Storage instructions | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
Target | C5aR2 |
Uniprot ID | Q9P296 |
Gene ID | 27202 |
Applications | FC, WB |
Working dilutions | Optimal dilution should be determined by the end user. |
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