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DLL4 antibody (MHD4-46) [PE]
Delta-like protein 4
Drosophila Delta homolog 4 (Delta4)
Gene name: DLL4
Drosophila Delta homolog 4 (Delta4)
Gene name: DLL4
As low as
$648.20
In stock
Ref
00118930
DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.
ID Covalab | mab21316 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | MHD4-46 |
Isotype | IgG1 kappa |
Raised in | Mouse |
Immunogen | The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development. |
Activity cross reaction | Recombinant soluble human DLL4. |
Species | Hu |
Labelling | ACE |
Form | Purified |
Preservative | NaN3 15 mM |
Storage instructions | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label. |
Target | DLL4 |
Uniprot ID | Q9NR61 |
Gene ID | 54567 |
Applications | FC |
Working dilutions | Optimal dilution should be determined by the end user. |
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