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Glucose Transporter GLUT4 antibody
Solute carrier family 2, facilitated glucose transporter member 4
Glucose transporter type 4, insulin-responsive (GLUT-4)
Gene name: SLC2A4, GLUT4
Glucose transporter type 4, insulin-responsive (GLUT-4)
Gene name: SLC2A4, GLUT4
As low as
$528.40
In stock
Ref
00096260
Glucose Transporter 4 (GLUT4/SLC2A4) is a member of a family of proteins that facilitate glucose transport. In response to insulin GLUT4 translocates from low density microsomes to the plasma membrane. Activation of phosphatidylinositol-3-OH kinase is required for this trafficking event but is not sufficient. Insulin resistant subjects with and without diabetes show abnormal accumulation of GLUT4 in a dense membrane compartment in muscle and adipocytes from which insulin is unable to recruit GLUT4 to the cell surface.
| ID Covalab | pab52658 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | A synthetic peptide made to an internal portion of the human GLUT4 protein (between residues 480-509) |
| Activity cross reaction | Reacts with human and mouse GLUT4 protein. May cross react with rat (100% sequence homology). |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.05% |
| Storage instructions | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Target | Glucose Transporter GLUT4 |
| Uniprot ID | P14672 |
| Applications | ICC, IF, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - ICC : 1/100 - IF : 1/100 - IHC : 1/200 - WB : 0.5µg/ml |
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