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XIAP antibody
Baculoviral IAP repeat-containing protein 4
E3 ubiquitin-protein ligase XIAP
IAP-like protein, ILP, hILP
Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3
X-linked inhibitor of apoptosis protein, X-linked IAP
Gene name: XIAP, API3, BIRC4, IAP3
E3 ubiquitin-protein ligase XIAP
IAP-like protein, ILP, hILP
Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3
X-linked inhibitor of apoptosis protein, X-linked IAP
Gene name: XIAP, API3, BIRC4, IAP3
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00099223
The human X chromosome linked Inhibitor of Apoptosis Protein (XIAP) is a major member of the inhibitor of apoptosis (IAP) family. XIAP functions by direct binding and inhibition of several caspases, including Caspase 3, Caspase 7 and Caspase 9. During apoptosis XIAP is specifically cleaved by Caspase 3 and partially loses its function. In addition to blocking the apoptosis signaling pathway, XIAP can also bind several other proteins in the bone morphogenetic protein (BMP) signaling pathway and act as a coupler between the membrane BMP receptor and the TAB1 TAK1 complex by binding to these proteins.
| ID Covalab | pab51048 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Isotype | IgG |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide corresponding to a portion of human ILP-2. |
| Activity cross reaction | Reacts with human XIAP protein. |
| Species | Hu |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Baculoviral IAP repeat-containing protein 4 |
| Uniprot ID | P98170 |
| Applications | WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1:100 - 1:2000) |
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