FK-506 (FK1) antibody

Tacrolimus
Fujimycin

CAS : 109581-93-3
C44H69NO12 . H2O
As low as $531.30
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00098503
FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/ml and depends on the patient's liver function, the nature of organ transplantation, and the time after transplantation.
More Information
ID Covalab mab60582
Product type Primary antibodies
Clonality Monoclonal antibody
Clone FK1
Isotype IgM
Raised in Mouse
Immunogen FK-506 conjugated to bovine serum albumin.
Activity cross reaction Reacts with conjugated and non-conjugated FK-506 (Kd=10E-9M)
Species No
Labelling None
Form Purified
Preservative NaN3 0.1%
Storage instructions Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Target FK-506
Applications ELISA, WB
Working dilutions Optimal dilution should be determined by the end user.
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