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FK-506 (FK1) antibody
Tacrolimus
Fujimycin
CAS : 109581-93-3
C44H69NO12 . H2O
Fujimycin
CAS : 109581-93-3
C44H69NO12 . H2O
As low as
$531.30
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00098503
FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/ml and depends on the patient's liver function, the nature of organ transplantation, and the time after transplantation.
| ID Covalab | mab60582 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | FK1 |
| Isotype | IgM |
| Raised in | Mouse |
| Immunogen | FK-506 conjugated to bovine serum albumin. |
| Activity cross reaction | Reacts with conjugated and non-conjugated FK-506 (Kd=10E-9M) |
| Species | No |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.1% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | FK-506 |
| Applications | ELISA, WB |
| Working dilutions | Optimal dilution should be determined by the end user. |
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