Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
|Product type||Primary antibodies|
|Immunogen||Synthetic peptide corresponding to an internal region of human TLR8.|
|Activity cross reaction||Reacts with human and mouse TLR8. Do not cross react with TLR7.|
|Storage instructions||Short term storage at +4°C.
For extended periods store in aliquots at -70°C.
Antibodies are guaranteed for 6 month from date of receipt.
|Target||Toll-like Receptor 8, TLR8|
|Applications||ELISA, IHC, WB|
|Working dilutions||Optimal dilution should be determined by the end user.
The following are guidelines only:
WB (1:500 - 1:2000)
ELISA (1:2000 - 1:10000)
IHC-P (5 ug/ml).
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