Toll-like Receptor 8 (TLR8) antibody

Toll-like Receptor 8, TLR8
Toll like receptor 8
CD288
Gene name: TLR8
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00098034
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
More Information
ID Covalab pab60328
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide corresponding to an internal region of human TLR8.
Activity cross reaction Reacts with human and mouse TLR8. Do not cross react with TLR7.
Species Hu, Ms
Labelling None
Form Purified
Preservative 0.01% NaN3
Storage instructions Short term storage at +4°C.
For extended periods store in aliquots at -70°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Toll-like Receptor 8, TLR8
Uniprot ID Q9NR97
Gene ID 51311
Applications ELISA, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
WB (1:500 - 1:2000)
ELISA (1:2000 - 1:10000)
IHC-P (5 ug/ml).
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