FLIP gamma/delta (C-Terminus) antibody

CASP8 and FADD-like apoptosis regulator
Caspase homolog, CASH
Caspase-eight-related protein, Casper
Caspase-like apoptosis regulatory protein, CLARP
Cellular FLICE-like inhibitory protein, c-FLIP
FADD-like antiapoptotic molecule 1, FLAME-1
Inhibitor of FLICE, I-FLICE
MACH-related inducer of toxicity, MRIT
Gene name: CFLAR, CASH, CASP8AP1, CLARP, MRIT
As low as $400.00
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00097848
FLIP contains two death effector domains and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and -10 and potently inhibits apoptosis induced by death receptors CD95, DR3, TRAIL-R, and TNFR1. Four splice variants of FLIP have been identified and designated FLIP alpha, beta, gamma and delta.
More Information
ID Covalab pab60142
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Peptide corresponding to aa 191-209 at the C-terminus of human FLIPg /FLIP-S form (accession no. AAC51623).
Activity cross reaction Reacts with the C-terminus part of human human FLIP gamma (35kDa)
and FLIP delta (25kDa) but not FLIP alpha or FLIP beta.
Species Hu
Labelling None
Form Purified
Preservative NaN3 0.02%
Storage instructions Store in aliquots at -20°C.
Antibodies are guaranteed for 6 months from date of receipt.
Target FLIP gamma/delta
Uniprot ID O15519
Gene ID 8837
Applications ICC, WB
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
ICC 1 µg/ml
WB 2 µg/ml
Positive control HeLa cells
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