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FLIP gamma/delta (C-Terminus) antibody
CASP8 and FADD-like apoptosis regulator
Caspase homolog, CASH
Caspase-eight-related protein, Casper
Caspase-like apoptosis regulatory protein, CLARP
Cellular FLICE-like inhibitory protein, c-FLIP
FADD-like antiapoptotic molecule 1, FLAME-1
Inhibitor of FLICE, I-FLICE
MACH-related inducer of toxicity, MRIT
Gene name: CFLAR, CASH, CASP8AP1, CLARP, MRIT
Caspase homolog, CASH
Caspase-eight-related protein, Casper
Caspase-like apoptosis regulatory protein, CLARP
Cellular FLICE-like inhibitory protein, c-FLIP
FADD-like antiapoptotic molecule 1, FLAME-1
Inhibitor of FLICE, I-FLICE
MACH-related inducer of toxicity, MRIT
Gene name: CFLAR, CASH, CASP8AP1, CLARP, MRIT
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00097848
FLIP contains two death effector domains and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and -10 and potently inhibits apoptosis induced by death receptors CD95, DR3, TRAIL-R, and TNFR1. Four splice variants of FLIP have been identified and designated FLIP alpha, beta, gamma and delta.
| ID Covalab | pab60142 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Peptide corresponding to aa 191-209 at the C-terminus of human FLIPg /FLIP-S form (accession no. AAC51623). |
| Activity cross reaction | Reacts with the C-terminus part of human human FLIP gamma (35kDa) and FLIP delta (25kDa) but not FLIP alpha or FLIP beta. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt. |
| Target | FLIP gamma/delta |
| Uniprot ID | O15519 |
| Gene ID | 8837 |
| Applications | ICC, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: ICC 1 µg/ml WB 2 µg/ml |
| Positive control | HeLa cells |
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