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DRAK1 (N-Terminus) antibody
Serine/threonine-protein kinase 17A
DAP kinase-related apoptosis-inducing protein kinase 1
Gene name: STK17A, DRAK1
DAP kinase-related apoptosis-inducing protein kinase 1
Gene name: STK17A, DRAK1
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00097830
Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.
Two novel serine/threonine kinases that induce apoptosis have been identified and designated DRAK1 and DRAK2 for DAP kinase–related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases which mediate apoptosis through their catalytic activities. DRAK1 is located in cell nuclei, and the mRNA for DRAK1 is ubiquitously expressed in human tissues.
Two novel serine/threonine kinases that induce apoptosis have been identified and designated DRAK1 and DRAK2 for DAP kinase–related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases which mediate apoptosis through their catalytic activities. DRAK1 is located in cell nuclei, and the mRNA for DRAK1 is ubiquitously expressed in human tissues.
| ID Covalab | pab60124 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Peptide corresponding to N-terminus part (aa 5-19) of human DRAK1. |
| Activity cross reaction | Reacts with human DRAK1. No cross-reactivity with DRAK2, DAP or ZIP kinases. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | DRAK1 |
| Uniprot ID | Q9UEE5 |
| Gene ID | 9263 |
| Applications | ICC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: ICC (2 µg/ml) WB (1 µg/ml) |
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