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TrpV3 Cation Channel (S15-39) antibody
Transient receptor potential cation channel subfamily V member 3, TrpV3
Vanilloid receptor-like 3, VRL-3
Gene name: TRPV3, OLMS, VRL3, FNEPPK2
Vanilloid receptor-like 3, VRL-3
Gene name: TRPV3, OLMS, VRL3, FNEPPK2
As low as
$669.90
In stock
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00097042
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. TrpV3 is in a family of nonselective cation channels that function in a variety of processes including temperature sensation and vaso-regulation. The thermosensitive members of this family are expressed in sensory neurons that terminate in the skin and is activated at temperatures between 22-40°C. TrpV3 might associate with TrpV1 to form heteromeric channels.
| ID Covalab | mab60529 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | S15-39 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Synthetic peptide corresponding to aa 458-474 (cytoplasmic C-terminus) of rat TrpV3 (accession no. NP_001020928). This sequence is 77% homologous with human and 100% homologous with mouse TrpV3. |
| Activity cross reaction | Reacts with human, mouse and rat TrpV3 Cation Channel. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.09% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | TrpV3 Cation Channel |
| Uniprot ID | Q8NET8 |
| Gene ID | 162514 |
| Applications | FC, ICC, IF, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1 - 10 µg/ml) ICC/IF (0.1 - 1.0 µg/ml) IP (1:10 - 1:500) FC (0.1- 1 µg for 10E6 cells) |
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