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Hsp70/Hsc70 (N27F3-4) antibody
Heat shock 70 kDa protein 1A/1B
Heat shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2
Heat shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2
As low as
$622.60
In stock
Ref
00096769
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
| ID Covalab | mab60256 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | N27F3-4 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Recombinant Hsp70/Hsc70 <br/><br/>Reacts with inducible and constitutive Hsp70/Hsc70 of human, mouse, rat, rabbit, monkey, guinea pig, hamster, chicken, bovine, canine, ovine, porcine, fish, Xenopus, Drosophila, C. elegans, and plants. The epitope is in the region of amino acids 503-640 of human Hsp70. |
| Activity cross reaction | Reacts with inducible and constitutive Hsp70/Hsc70 of human, mouse, rat, rabbit, monkey, guinea pig, hamster, chicken, bovine, canine, ovine, porcine, fish, Xenopus, Drosophila, C. elegans, and plants. The epitope is in the region of amino acids 503-640 of human Hsp70. |
| Species | Chick, D. mel., Fi, Hu, Ma, Xe |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.1% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt. |
| Target | Hsp70/Hsc70 |
| Uniprot ID | P08107 |
| Gene ID | 3304 |
| Applications | FC, IHC, IP, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: WB 1 µg/ml IHC 1-10 µg/ml IP 1-10 µg/ml FC 10 µg/ml |
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