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Hsc70 (Hsp73) (1F2.H5) antibody
Heat shock cognate 71 kDa protein
Heat shock 70 kDa protein 8
Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1
Gene name: HSPA8, HSC70, HSP73, HSPA10
Heat shock 70 kDa protein 8
Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1
Gene name: HSPA8, HSC70, HSP73, HSPA10
As low as
$550.00
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00096750
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
| ID Covalab | mab60237 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 1F2.H5 |
| Isotype | IgG2a |
| Raised in | Mouse |
| Immunogen | Human Hsc70 |
| Activity cross reaction | Reacts with human, mouse and rat Hsc70. Does not cross-react with Hsp70. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | None |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt. |
| Target | Hsc70 (Hsp73) |
| Uniprot ID | P11142 |
| Gene ID | 3312 |
| Applications | ELISA, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : WB (1 µg/ml ELISA (1 - 10 µg/ml) IHC (1 - 10 µg/ml) IP (1 - 10 µg/ml) |
| Positive control | HeLa cells |
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