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GIT1 (S39B-8) antibody
ARF GTPase-activating protein GIT1, ARF GAP GIT1
Cool-associated and tyrosine-phosphorylated protein 1, CAT-1, CAT1
G protein-coupled receptor kinase-interactor 1
GRK-interacting protein 1
Gene name : GIT1
Cool-associated and tyrosine-phosphorylated protein 1, CAT-1, CAT1
G protein-coupled receptor kinase-interactor 1
GRK-interacting protein 1
Gene name : GIT1
As low as
$669.90
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00096699
G-protein coupled receptor (GPCR) kinase interacting proteins 1 and 2 (GIT1 and GIT2) are highly conserved ubiquitous scaffold proteins involved in localized signaling to help regulate focal contact assembly and cytoskeletal dynamics. GIT proteins contain multiple interaction domains for small GTPases, kinases, the Rho family GEF PIX, and the focal adhesion protein paxillin. GIT1 is localized to focal adhesions, cytoplasmic complexes and membrane protrusions, and it regulates cell protrusion formation and cell migration.
| ID Covalab | mab60186 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | S39B-8 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Fusion protein corresponding to aa 375-770 (C-terminus) of rat GIT1 (accession no.Q9Z272). |
| Activity cross reaction | Reacts with human GIT1. Cross-reacts with mouse and rat protein. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.09% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | GIT1 |
| Uniprot ID | Q9Y2X7 |
| Gene ID | 28964 |
| Applications | WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : WB (1 µg/ml) |
| Positive control | Rat brain lysate. |
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