GABA(B)R2 (S81-2) antibody

Gamma-aminobutyric acid type B receptor subunit 2
GABA-B receptor 2
GABA-B-R2, GABA-BR2, GABABR2, Gb2
G-protein coupled receptor 51
HG20
Gene name : GABBR2
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00096698
GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B), and GABA(C). GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 in which GABA(B)R1 binds a ligand and GABA(B)R2 is the primary G protein contact site.
More Information
ID Covalab mab60185
Product type Primary antibodies
Clonality Monoclonal antibody
Clone S81-2
Isotype IgG1
Raised in Mouse
Immunogen Fusion protein corresponding to aa 861-912 of rat GABA(B)R2 (accession no. NP_113990.1).
Activity cross reaction Reacts with human GABA(B)R2. Cross-reacts with mouse and rat protein. Do not cross-react with GABA(B)R1.
Species Hu, Ms, Rat
Labelling None
Form Purified (protein G)
Preservative NaN3 0,09%
Storage instructions Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Target GABA(B)R2
Uniprot ID O75899
Gene ID 9568
Applications IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC (1 -5 µg/ml)
WB (1 - 2 µg/ml)
Positive control Rat brain membranes.
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