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GABA(B)R2 (S81-2) antibody
Gamma-aminobutyric acid type B receptor subunit 2
GABA-B receptor 2
GABA-B-R2, GABA-BR2, GABABR2, Gb2
G-protein coupled receptor 51
HG20
Gene name : GABBR2
GABA-B receptor 2
GABA-B-R2, GABA-BR2, GABABR2, Gb2
G-protein coupled receptor 51
HG20
Gene name : GABBR2
As low as
$669.90
In stock
Ref
00096698
GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B), and GABA(C). GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 in which GABA(B)R1 binds a ligand and GABA(B)R2 is the primary G protein contact site.
| ID Covalab | mab60185 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | S81-2 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Fusion protein corresponding to aa 861-912 of rat GABA(B)R2 (accession no. NP_113990.1). |
| Activity cross reaction | Reacts with human GABA(B)R2. Cross-reacts with mouse and rat protein. Do not cross-react with GABA(B)R1. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0,09% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | GABA(B)R2 |
| Uniprot ID | O75899 |
| Gene ID | 9568 |
| Applications | IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC (1 -5 µg/ml) WB (1 - 2 µg/ml) |
| Positive control | Rat brain membranes. |
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