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GABA(B)R1 (S93A-49) antibody
Gamma-aminobutyric acid type B receptor subunit 1
GABA-B receptor 1, GABA-B-R1
GABA-BR1
GABABR1, Gb1
Gene name : GABBR1
GABA-B receptor 1, GABA-B-R1
GABA-BR1
GABABR1, Gb1
Gene name : GABBR1
As low as
$669.90
In stock
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00096697
GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B), and GABA(C). GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 in which GABA(B)R1 binds a ligand and GABA(B)R2 is the primary G protein contact site.
ID Covalab | mab60184 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | S93A-49 |
Isotype | IgG1 |
Raised in | Mouse |
Immunogen | Fusion protein corresponding to aa 873-977 (cytoplasmic C-terminus) of rat GABA(B)R1 (accession no. NP_112290.2). |
Activity cross reaction | Reacts with human GABA(B)R1. Cross-reacts with mouse and rat protein. Do not cross-react with GABA(B)R2. |
Species | Hu, Ms, Rat |
Labelling | None |
Form | Purified (protein G) |
Preservative | NaN3 0.09% |
Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
Target | GABA(B)R1 |
Uniprot ID | Q9UBS5 |
Gene ID | 2550 |
Applications | ICC, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ICC (1 - 5 µg/ml) WB (1 - 2 µg/ml) |
Positive control | Rat brain membranes. |
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