GABA(B)R1 (S93A-49) antibody

Gamma-aminobutyric acid type B receptor subunit 1
GABA-B receptor 1, GABA-B-R1
GABA-BR1
GABABR1, Gb1
Gene name : GABBR1
As low as $669.90
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00096697
GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B), and GABA(C). GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 in which GABA(B)R1 binds a ligand and GABA(B)R2 is the primary G protein contact site.
More Information
ID Covalab mab60184
Product type Primary antibodies
Clonality Monoclonal antibody
Clone S93A-49
Isotype IgG1
Raised in Mouse
Immunogen Fusion protein corresponding to aa 873-977 (cytoplasmic C-terminus) of rat GABA(B)R1 (accession no. NP_112290.2).
Activity cross reaction Reacts with human GABA(B)R1. Cross-reacts with mouse and rat protein. Do not cross-react with GABA(B)R2.
Species Hu, Ms, Rat
Labelling None
Form Purified (protein G)
Preservative NaN3 0.09%
Storage instructions Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Target GABA(B)R1
Uniprot ID Q9UBS5
Gene ID 2550
Applications ICC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC (1 - 5 µg/ml)
WB (1 - 2 µg/ml)
Positive control Rat brain membranes.
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