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Factor V Heavy Chain (B10) antibody
Coagulation factor V
Activated protein C cofactor
Proaccelerin, labile factor
Coagulation factor V heavy chain
FVL
PCCF
THPH2
RPRGL1
Gene name : F5
Activated protein C cofactor
Proaccelerin, labile factor
Coagulation factor V heavy chain
FVL
PCCF
THPH2
RPRGL1
Gene name : F5
As low as
$748.00
In stock
Ref
00096672
Factor V is an essential cofactor of the blood coagulation cascade and a central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions.
| ID Covalab | mab60159 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | B10 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Purified human Factor V. |
| Activity cross reaction | Reacts with human thrombin-cleaved Factor V Heavy Chain. KD = 1.15 x 10.-10 mol/L. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | None |
| Storage instructions | Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles. |
| Target | Factor V Heavy Chain |
| Uniprot ID | P12259 |
| Gene ID | 2153 |
| Applications | ELISA, IHC, RIA |
| Working dilutions | Optimal dilution should be determined by the end user. |
| Publication | Gewirtz AM, et al. Biology of human megakaryocyte factor V. Blood. 1986 Jun,67(6):1639-48. |
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