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Cavβ2 Ca+2 Channel (S8b-1) antibody
Voltage-dependent L-type calcium channel subunit beta-2, CAB2
Calcium channel voltage-dependent subunit beta 2
Lambert-Eaton myasthenic syndrome antigen B, MYSB
calcium channel, voltage-dependent, beta 2 subunit
Gene name: CACNB2, CACNLB2, MYSB, CAVB2
Calcium channel voltage-dependent subunit beta 2
Lambert-Eaton myasthenic syndrome antigen B, MYSB
calcium channel, voltage-dependent, beta 2 subunit
Gene name: CACNB2, CACNLB2, MYSB, CAVB2
As low as
$669.90
In stock
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00096583
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cavβ subunits are involved in the transport of the pore-forming alpha1 subunit to the plasma membrane. They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the poreforming subunit to the target membrane.
| ID Covalab | mab60070 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | S8b-1 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Synthetic peptide corresponding to aa 189-205 of rat Cavβ2 (RSPKPSANSVTSPHSKE) (accession no. NP_446303). |
| Activity cross reaction | Reacts with human, mouse and rat Cavβ2 Ca+2 Channel. It does not cross-react with Cav β1, Cav β3, or Cav β4. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.09% |
| Storage instructions | Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles. |
| Target | Cavβ2 Ca+2 Channel |
| Uniprot ID | Q08289 |
| Gene ID | 783 |
| Applications | ICC, IF, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1 - 10 µg/ml) ICC (0.1 - 1 µg/ml) IF (1 - 10 µg/ml) |
| Positive control | Adult rat brain |
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