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Metabotropic Glutamate Receptor 2/3 antibody
Metabotropic glutamate receptor 2, mGluR2
Gene name: GRM2, Gprc1b, Mglur2
Gene name: GRM2, Gprc1b, Mglur2
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$528.40
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00029085
Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
| ID Covalab | pab50514 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide corresponding to residues 860-875 of the rat mGlurR2/3 protein. |
| Activity cross reaction | Reacts with rat mGluR2/3. Predicted react to human and mouse. |
| Species | Rat |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Metabotropic Glutamate Receptor 2/3 (mGluR2/3) |
| Uniprot ID | P31421 |
| Applications | IHC, IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC (1:10 - 1:2000) |
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