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MAPK3 / ERK1 (aa350-400) antibody
Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3
ERT2
Extracellular signal-regulated kinase 1, ERK-1
Insulin-stimulated MAP2 kinase
MAP kinase isoform p44, p44-MAPK
Microtubule-associated protein 2 kinase
p44-ERK1
Gene name: MAPK3, ERK1, PRKM3
ERT2
Extracellular signal-regulated kinase 1, ERK-1
Insulin-stimulated MAP2 kinase
MAP kinase isoform p44, p44-MAPK
Microtubule-associated protein 2 kinase
p44-ERK1
Gene name: MAPK3, ERK1, PRKM3
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00024290
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.
| ID Covalab | pab74613 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Isotype | IgG |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from human MAPK3 / ERK1. |
| Activity cross reaction | Reacts with human MAPK3 / ERK1. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.05% |
| Storage instructions | Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. |
| Target | MAPK3 / ERK1 |
| Uniprot ID | P27361 |
| Gene ID | 5595 |
| Applications | IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC-P (10 µg/ml), WB (1 - 3 µg/ml) |
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