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DSP / Desmoplakin (Internal) antibody
DSP, Apeg-1, Apeg-1 protein, Desmoplakin i, Desmoplakin II, DP, DPI, DPII
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00023575
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
| ID Covalab | pab74221 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Goat |
| Immunogen | Synthetic peptide C-QESVKQAHLRNEH from an internal region of human DSP / Desmoplakin (NP_004406.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Marmoset (100%), Monkey (92%), Mouse (92%) |
| Activity cross reaction | Reacts with human DSP / Desmoplakin. Cross reacts with mouse and rat protein. This antibody is expected to recognize reported isoform I (NP_004406.2) only. |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Store at -20°C. Minimize freezing and thawing. |
| Target | DSP / Desmoplakin |
| Accession Number | P15924 |
| Applications | ELISA, IHC - P |
| Working dilutions | ELISA (1:4000), IHC-P (3.75 µg/ml) |
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