We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
ATG4D (C-Terminus) antibody
Cysteine protease ATG4D, AUT-like 4 cysteine endopeptidase, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, Cysteine protease ATG4D, mitochondrial
Gene name: ATG4D, APG4-D, APG4D, AUTL4
Gene name: ATG4D, APG4-D, APG4D, AUTL4
Out of stock
Ref
00023102
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.
| ID Covalab | pab73953 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Goat |
| Immunogen | Synthetic peptide CSQLAQPTLRLPRT from an internal region (near C-terminus) of human ATG4D (NP_116274.3). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (93%), Monkey (93%), Marmoset (93%), Panda (93%) |
| Activity cross reaction | Reacts with the C-terminus part of human and gorilla ATG4D. Predicted to ross reacts with gibbon, monkey, dog and horse protein. |
| Species | Hu, Mk |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Store at -20°C. Minimize freezing and thawing. |
| Target | ATG4D |
| Uniprot ID | Q86TL0 |
| Gene ID | 84971 |
| Applications | ELISA, IHC - P |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ELISA (1:32000), IHC-P (2.5 - 3.75 µg/ml) |
Write Your Own Review