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SIRT2 (N-Terminus) antibody
NAD-dependent protein deacetylase sirtuin-2
Regulatory protein SIR2 homolog 2
SIR2-like protein 2
Gene name: SIRT2, SIR2L, SIR2L2
Regulatory protein SIR2 homolog 2
SIR2-like protein 2
Gene name: SIRT2, SIR2L, SIR2L2
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00021486
NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins such as ACLY, PCK1 and RELA. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.
ID Covalab | pab73213 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | 17 amino acid peptide near the amino terminus of the human SIRT2. |
Activity cross reaction | Reacts with human, mouse and rat SIRT2. |
Species | Hu, Ms, Rat |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.02% |
Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Target | SIRT2 |
Uniprot ID | Q8IXJ6 |
Gene ID | 22933 |
Applications | ELISA, IHC - P, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC-P (5 µg/ml), WB (2.5 - 5 µg/ml) |
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