SIRT2 (N-Terminus) antibody

NAD-dependent protein deacetylase sirtuin-2
Regulatory protein SIR2 homolog 2
SIR2-like protein 2
Gene name: SIRT2, SIR2L, SIR2L2
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00021486
NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins such as ACLY, PCK1 and RELA. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.
More Information
ID Covalab pab73213
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen 17 amino acid peptide near the amino terminus of the human SIRT2.
Activity cross reaction Reacts with human, mouse and rat SIRT2.
Species Hu, Ms, Rat
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Target SIRT2
Uniprot ID Q8IXJ6
Gene ID 22933
Applications ELISA, IHC - P, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (5 µg/ml),
WB (2.5 - 5 µg/ml)
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