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P2RX7 / P2X7 (aa13-26) antibody
P2X purinoceptor 7, P2X7, ATP receptor, P2Z receptor, Purinergic receptor
MGC20089, P2X receptor 7, P2X7, P2X7 purinoceptor
Gene names: P2RX7
MGC20089, P2X receptor 7, P2X7, P2X7 purinoceptor
Gene names: P2RX7
Out of stock
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00021405
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
| ID Covalab | pab73132 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Goat |
| Immunogen | Synthetic peptide YETNKVTRIQSMNY-C from the N-terminus (aa13-26) of human P2RX7 / P2X7 (NP_002553.2). Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Hamster, Pig (100%), Monkey, Mouse, Rat, Guinea pig (93%), Elephant, Panda, Dog, Rabbit (86%). |
| Activity cross reaction | Reacts with P2RX7 from human, hamster, pig. Predicted to cross react with monkey, mouse, rat, guinea pig. |
| Species | Ham, Hu, Po |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Store at -20°C. Minimize freezing and thawing. |
| Target | P2RX7 / P2X7 |
| Uniprot ID | Q99572 |
| Gene ID | 5027 |
| Applications | ELISA, IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : ELISA (1:16000) IHC-P (3.75 µg/ml) WB (1 - 3 µg/ml) |
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