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PARK7 / DJ-1 (aa167-189) antibody
Protein DJ-1
Oncogene DJ1
Parkinson disease protein 7
Gene name: PARK7
Oncogene DJ1
Parkinson disease protein 7
Gene name: PARK7
Out of stock
Ref
00019325
Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
| ID Covalab | pab72052 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Isotype | IgG |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from residues 167-189 (AIVEALNGKEVAAQVKAPLVLKD) of human PARK7 (DJ-1) |
| Activity cross reaction | Reacts with PARK7 (DJ-1) from human, gorilla, gibbon. May cross reacts with protein from monkey, horse, rabbit. |
| Species | Hu, Mk |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Target | PARK7 / DJ-1 |
| Uniprot ID | Q99497 |
| Gene ID | 11315 |
| Applications | ELISA, IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC-P (10 µg/ml), WB (1:500 - 1:1000) |
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