We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
MAPK3 / ERK1 (Internal) antibody
Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3
ERT2
Extracellular signal-regulated kinase 1, ERK-1
Insulin-stimulated MAP2 kinase
MAP kinase isoform p44, p44-MAPK
Microtubule-associated protein 2 kinase
p44-ERK1
Gene name: MAPK3, ERK1, PRKM3
ERT2
Extracellular signal-regulated kinase 1, ERK-1
Insulin-stimulated MAP2 kinase
MAP kinase isoform p44, p44-MAPK
Microtubule-associated protein 2 kinase
p44-ERK1
Gene name: MAPK3, ERK1, PRKM3
As low as
$573.50
In stock
Ref
00018579
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.
| ID Covalab | pab71687 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic 18 amino acid peptide from internal region of human MAPK3 / ERK1. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Bovine, Dog (100%) |
| Activity cross reaction | Reacts with MAPK3 / ERK1 from Human, Gorilla, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MAPK1 (61%). |
| Species | Hu, Ma, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.1% |
| Storage instructions | Long term: -70°C; Short term: +4°C |
| Target | MAPK3 / ERK1 |
| Uniprot ID | P27361 |
| Gene ID | 5595 |
| Applications | IHC - P |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC-P (7 µg/ml) |
Write Your Own Review