BACE1 (N-Terminus) antibody

Beta-secretase 1
Aspartyl protease 2 (ASP2) (Asp 2)
Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1)
Memapsin-2
Membrane-associated aspartic protease 2
BACE1, BACE, KIAA1149, APP beta-secretase, ASP2, Aspartylprotease 2, B-Secretase, Beta-site app cleaving enzyme, FLJ90568, HSPC104
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00015852
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
More Information
ID Covalab pab70381
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic 18 amino acid peptide from Near the N-terminus of human BACE1. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Mouse (94%), Rat (94%), Dog (94%), Bat (94%), ...
Activity cross reaction Reacts with human BACE1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CPD (39%).
Species Hu
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.1%
Storage instructions Long term: -70°C; Short term: +4°C
Target BACE1
Accession Number P56817
Applications IHC - P
Working dilutions IHC - P (5 µg/ml)
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