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ATG7 (C-Terminus) antibody
Ubiquitin-like modifier-activating enzyme ATG7
ATG12-activating enzyme E1 ATG7
Autophagy-related protein 7 (APG7-like) (hAGP7)
Ubiquitin-activating enzyme E1-like protein
Gene name: ATG7, APG7-LIKE, APG7L, DKFZp434N0735, GSA7
ATG12-activating enzyme E1 ATG7
Autophagy-related protein 7 (APG7-like) (hAGP7)
Ubiquitin-activating enzyme E1-like protein
Gene name: ATG7, APG7-LIKE, APG7L, DKFZp434N0735, GSA7
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00015827
Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3
| ID Covalab | pab70356 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from human ATG7. |
| Activity cross reaction | Reacts with 17 amino acid peptide from near the carboxy terminus of human APG7. |
| Species | Hu, Ms |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | ATG7 |
| Uniprot ID | O95352 |
| Gene ID | 10533 |
| Applications | ICC, IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC - P (5 µg/ml), WB (0.5 - 1 µg/ml) |
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