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ATG16L1 (N-Terminus) antibody
Autophagy-related protein 16-1
APG16-like 1
Gene name: ATG16L1, APG16L, ATG16A, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30
APG16-like 1
Gene name: ATG16L1, APG16L, ATG16A, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30
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00015826
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
ID Covalab | pab70355 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | 18 amino acid peptide from near the amino terminus of human ATG16. |
Activity cross reaction | Reacts with ATG16L1 from human, mouse and rat |
Species | Hu, Ms, Rat |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.02% |
Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Target | ATG16L1 |
Uniprot ID | Q676U5 |
Gene ID | 55054 |
Applications | ELISA, ICC, IF, IHC - P, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC - P (5 µg/ml) ICC/IF (4.75 µg/ml) WB (0.5 - 1 µg/ml) |
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