ATG16L1 (N-Terminus) antibody

Autophagy-related protein 16-1
APG16-like 1
Gene name: ATG16L1, APG16L, ATG16A, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30
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Ref
00015826
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
More Information
ID Covalab pab70355
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen 18 amino acid peptide from near the amino terminus of human ATG16.
Activity cross reaction Reacts with ATG16L1 from human, mouse and rat
Species Hu, Ms, Rat
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Target ATG16L1
Uniprot ID Q676U5
Gene ID 55054
Applications ELISA, ICC, IF, IHC - P, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC - P (5 µg/ml)
ICC/IF (4.75 µg/ml)
WB (0.5 - 1 µg/ml)
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