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ATF6 (N-Terminus) antibody
Cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha
Activating transcription factor 6 alpha, ATF6-alpha
Gene name: ATF6, ATF6A
Activating transcription factor 6 alpha, ATF6-alpha
Gene name: ATF6, ATF6A
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00015822
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor
ID Covalab | pab70351 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Synthetic peptide from near the amino terminus of human ATF6. |
Activity cross reaction | Reacts with human and mouse ATF6 |
Species | Hu, Ms |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.02% |
Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Target | ATF6 |
Uniprot ID | P18850 |
Applications | ELISA, ICC, IHC - P, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: IHC - P (5 µg/ml) WB (0.5 - 1 µg/ml) |
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