ATF6 (N-Terminus) antibody

Cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha
Activating transcription factor 6 alpha, ATF6-alpha
Gene name: ATF6, ATF6A
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00015822
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor
More Information
ID Covalab pab70351
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide from near the amino terminus of human ATF6.
Activity cross reaction Reacts with human and mouse ATF6
Species Hu, Ms
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Target ATF6
Uniprot ID P18850
Applications ELISA, ICC, IHC - P, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC - P (5 µg/ml)
WB (0.5 - 1 µg/ml)
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