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ANAPC11 / APC11 (Internal) antibody
Anaphase-promoting complex subunit 11 (APC11)
Cyclosome subunit 11
Hepatocellular carcinoma-associated RING finger protein
ANAPC11, APC11, Apc11p, HSPC214, MGC882
Cyclosome subunit 11
Hepatocellular carcinoma-associated RING finger protein
ANAPC11, APC11, Apc11p, HSPC214, MGC882
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00015785
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
| ID Covalab | pab70314 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | 18 amino acid peptide near the center of human APC11. |
| Activity cross reaction | Reacts with human ANAPC11 |
| Species | Hu, Ms, Rat |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | ANAPC11 / APC11 |
| Accession Number | Q9NYG5 |
| Applications | ELISA, IHC - P, WB |
| Working dilutions | ELISA, IHC - P (5 µg/ml), WB (1 - 2 µg/ml) |
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