ANAPC11 / APC11 (Internal) antibody

Anaphase-promoting complex subunit 11 (APC11)
Cyclosome subunit 11
Hepatocellular carcinoma-associated RING finger protein
ANAPC11, APC11, Apc11p, HSPC214, MGC882
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00015785
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
More Information
ID Covalab pab70314
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen 18 amino acid peptide near the center of human APC11.
Activity cross reaction Reacts with human ANAPC11
Species Hu, Ms, Rat
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Target ANAPC11 / APC11
Accession Number Q9NYG5
Applications ELISA, IHC - P, WB
Working dilutions ELISA, IHC - P (5 µg/ml), WB (1 - 2 µg/ml)
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