AICDA (C-Terminus) antibody

Activation-induced cytidine deaminase
Cytidine aminohydrolase
Gene name : AICDA, AID
ARP2, CDA2, HIGM2
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00015770
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation
More Information
ID Covalab pab70299
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide from human AICDA.
Activity cross reaction Reacts with peptide corresponding to 14 amino acids near the carboxy-terminus of human AID
Species Hu, Ms
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Target AICDA
Accession Number Q9GZX7
Applications ICC, IHC - P, WB
Working dilutions ICC, IHC - P (5 µg/ml), WB (1 - 2 µg/ml)
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