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ACVR1C (Internal) antibody
Activin receptor type-1C
Activin receptor type IC (ACTR-IC)
Activin receptor-like kinase 7 (ALK-7)
ACVR1C, Activin Receptor-like Kinase, ACVRLK7, ALK7
Activin receptor type IC (ACTR-IC)
Activin receptor-like kinase 7 (ALK-7)
ACVR1C, Activin Receptor-like Kinase, ACVRLK7, ALK7
As low as
$573.50
In stock
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00015636
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
ID Covalab | pab70243 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Synthetic 16 amino acid peptide from internal region of human ACVR1C. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Bovine (100%), Bat (100%), Pig (100%), Marmoset (94%), Elephant ( ... |
Activity cross reaction | Reacts with human ACVR1C. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Species | Hu |
Labelling | None |
Form | Antigen affinity purified |
Preservative | NaN3 0.1% |
Storage instructions | Long term: -70°C; Short term: +4°C |
Target | ACVR1C |
Accession Number | Q8NER5 |
Applications | IHC - P |
Working dilutions | IHC - P (5 µg/ml) |
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