ACVR1 / ALK2 (C-Terminus) antibody

Activin receptor type I (ACTR-I)
Activin receptor-like kinase 2 (ALK-2)
Serine/threonine-protein kinase receptor R1 (SKR1)
TGF-B superfamily receptor type I (TSR-I)
ACVR1, Activin A receptor type I, Actr1, ACTRI, ActRIA, ACVR1A, ACVRLK2, ALK2, FOP, Tsk7L, TSRI
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00015634
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis
More Information
ID Covalab pab70241
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic 14 amino acid peptide near the carboxy terminus of the human ACVR1B.
Activity cross reaction Reacts with human ACVR1B. Cross reacts with mouse protein.
Species Hu, Ms
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Target ACVR1 / ALK2
Accession Number Q04771
Applications IHC - P, WB
Working dilutions IHC - P (5 µg/ml), WB (1 µg/ml)
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