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LAR antibody (W7C6)
Receptor-type tyrosine-protein phosphatase F
Gene name: PTPRF
Gene name: PTPRF
As low as
$572.30
In stock
Ref
00118532
LAR is a receptore-linked transmembrane protein tyrosine phosphatase expressed on mesenchymal stem cells, that reside e.g. in bone marrow, blood, placenta, adipose tissue, or skin, as well as it is expressed on some carcinoma cell lines, including HeLa, MCF-7, or HT29. During the process of externalization, LAR is intracellularly proteolytically processed into two non-covalently associated subunits. This protein is involved in intercellular and cell-matrix interactions and its extracellular part resembles that of cell adhesion molecules (CAMs). The extracellular part can be released from the surface, which may be used for regulation of LAR function.
| ID Covalab | mab21295 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | W7C6 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | The mouse monoclonal antibody W7C6 recognizes an extracellular epitope of protein tyrosine phosphatase LAR, a marker of mesenchymal stem cells. |
| Activity cross reaction | WERI-RB-1 retinoblastoma cells |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | NaN3 15 mM |
| Storage instructions | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Target | LAR |
| Uniprot ID | G1UI20 |
| Gene ID | 5792 |
| Applications | FC |
| Working dilutions | Optimal dilution should be determined by the end user. |
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