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CD49e antibody (5H10-27 (MFR5)) [FITC]
Integrin alpha-5
CD49 antigen-like family member E
Fibronectin receptor subunit alpha
Integrin alpha-F
VLA-5
CD49e
Gene name: Itga5
CD49 antigen-like family member E
Fibronectin receptor subunit alpha
Integrin alpha-F
VLA-5
CD49e
Gene name: Itga5
As low as
$347.40
In stock
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00118523
CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis.
| ID Covalab | mab21290 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 5H10-27 (MFR5) |
| Isotype | IgG2a kappa |
| Raised in | Rat |
| Immunogen | The rat monoclonal antibody 5H10-27 (MFR5) recognizes an extracellular epitope of murine CD49e, a 135 kDa protein serving as VLA-5 alpha chain, expressed on thymocytes, activated T cells, splenic B cells, and mast cells. |
| Activity cross reaction | C57BL/6 x A/J)F1 murine mast cell line |
| Species | Ms |
| Labelling | FITC |
| Form | Purified |
| Preservative | NaN3 15 mM |
| Storage instructions | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Target | CD49e |
| Uniprot ID | P11688 |
| Gene ID | 16402 |
| Applications | FC |
| Working dilutions | Optimal dilution should be determined by the end user. |
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