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CD64 antibody (10.1) [PE]
High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I
Fc-gamma RI, FcRI
Fc-gamma RIA, FcgammaRIa
CD_antigen: CD64
Gene name: FCGR1A, FCG1, FCGR1, IGFR1
Fc-gamma RI, FcRI
Fc-gamma RIA, FcgammaRIa
CD_antigen: CD64
Gene name: FCGR1A, FCG1, FCGR1, IGFR1
As low as
$484.50
In stock
Ref
00114785
CD64 antibody (10.1) [PE]
| ID Covalab | mab21037 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 10.1 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Rheumatoid synovial fluid cells and fibronectin purified human monocytes |
| Activity cross reaction | Reacts with human alpha subunit of CD64. Cross-reacts with monkey protein. |
| Species | Hu, Mk |
| Labelling | PE |
| Form | Purified (liquid chromatography) |
| Preservative | NaN3 15 mM |
| Storage instructions | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
| Target | CD64 |
| Uniprot ID | P12314 |
| Gene ID | 2209 |
| Applications | FA, FC, ICC, IHC, IP, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: FC (10 µl for 100 µl of whole blood or 10^6 cells in suspension) |
| Publication | * Devaraj S et al. CRP promotes monocyte-endothelial cell adhesion via Fcgamma receptors in human aortic endothelial cells under static and shear flow conditions. Am J Physiol Heart Circ Physiol. 2006 Sep,291(3):H1170-6. * Roura-Mir C et al. Mycobacterium tuberculosis regulates CD1 antigen presentation pathways through TLR-2. J Immunol. 2005 Aug 1,175(3):1758-66. * Devaraj S et al. Binding and internalization of C-reactive protein by Fcgamma receptors on human aortic endothelial cells mediates biological effects. Arterioscler Thromb Vasc Biol. 2005 Jul,25(7):1359-63. *Beekman JM et al. Modulation of FcgammaRI (CD64) ligand binding by blocking peptides of periplakin. J Biol Chem. 2004 Aug 6,279(32):33875-81. * Sánchez-Torres C et al. CD16+ and CD16- human blood monocyte subsets differentiate in vitro to dendritic cells with different abilities to stimulate CD4+ T cells. Int Immunol. 2001 Dec,13(12):1571-81. * Brichard B et al. Intracellular cytokine profile of cord and adult blood monocytes. Bone Marrow Transplant. 2001 May,27(10):1081-6. * Fadlon E et al. Blood polymorphonuclear leukocytes from the majority of sickle cell patients in the crisis phase of the disease show enhanced adhesion to vascular endothelium and increased expression of CD64. Blood. 1998 Jan 1, 91(1):266-74. * Hashimoto S et al. Enhancement of macrophage colony-stimulating factor-induced growth and differentiation of human monocytes by interleukin-10. Blood. 1997 Jan 1,89(1):315-21. * Jayaram Yet al. The Fc receptor, FcRI, and other activation molecules on human mononuclear phagocytes after treatment with interferon-gamma. Clin Exp Immunol. 1989 Mar,75(3):414-20. * Dougherty GJ et al. The human mononuclear phagocyte high-affinity Fc receptor, FcRI, defined by a monoclonal antibody, 10.1. Eur J Immunol. 1987 Oct,17(10):1453-9. |
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