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CD14 antibody (MEM-15) [APC]
Monocyte differentiation antigen CD14
Myeloid cell-specific leucine-rich glycoprotein
CD_antigen: CD14
Gene name: CD14
Myeloid cell-specific leucine-rich glycoprotein
CD_antigen: CD14
Gene name: CD14
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00114407
CD14 antibody (MEM-15) [APC]
ID Covalab | mab20659 |
---|---|
Product type | Primary antibodies |
Clonality | Monoclonal antibody |
Clone | MEM-15 |
Isotype | IgG1 |
Raised in | Mouse |
Immunogen | Crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria. |
Activity cross reaction | Reacts with human CD14. Reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients. Cross-reacts with monkey protein. |
Species | Hu, Mk |
Labelling | APC |
Form | Purified (liquid chromatography) |
Preservative | NaN3 15 mM |
Storage instructions | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
Target | CD14 |
Uniprot ID | P08571 |
Gene ID | 929 |
Applications | FC, IP |
Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: FC (10 µl for 100 µl of whole blood or 10^6 cells in suspension) |
Publication | * Majer F et al. Danon disease: a focus on processing of the novel LAMP2 mutation and comments on the beneficial use of peripheral white blood cells in the diagnosis of LAMP2 deficiency. Gene. 2012 May 1,498(2):183-95. * Sing A et al. Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression. J Exp Med. 2002 Oct 21,196(8):1017-24. * Funda DP et al. CD14 is expressed and released as soluble CD14 by human intestinal epithelial cells in vitro: lipopolysaccharide activation of epithelial cells revisited. Infect Immun. 2001 Jun,69(6):3772-81. * Schiff DE et al. Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects. Blood. 1997 Oct 15,90(8):3187-94. * Bazil V et al. Biochemical characterization of a soluble form of the 53-kDa monocyte surface antigen. Eur J Immunol. 1986 Dec,16(12):1583-9. |
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