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CD14 antibody (MEM-18) [APC]
Monocyte differentiation antigen CD14
Myeloid cell-specific leucine-rich glycoprotein
CD_antigen: CD14
Gene name: CD14
Myeloid cell-specific leucine-rich glycoprotein
CD_antigen: CD14
Gene name: CD14
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00114406
CD14 antibody (MEM-18) [APC]
| ID Covalab | mab20658 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | MEM-18 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | Crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria. |
| Activity cross reaction | Reacts with a region within amino acids 57 to 64 of human and monkey CD14. |
| Species | Hu, Mk |
| Labelling | APC |
| Form | Purified (liquid chromatography) |
| Preservative | NaN3 15 mM |
| Storage instructions | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
| Target | CD14 |
| Uniprot ID | P08571 |
| Gene ID | 929 |
| Applications | ELISA, FA, FC, IP, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: FC (10 µl for 100 µl of whole blood or 10^6 cells in suspension) |
| Publication | * Weiss TS et al. Hepatic progenitor cells from adult human livers for cell transplantation. Gut. 2008 Aug,57(8):1129-38. * Angel CE et al. CD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts. Int Immunol. 2007 Nov,19(11):1271-9. * Drbal K et al. Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement. Int Immunol. 2007 May,19(5):675-84. * Iwaki D et al. The CD14 region spanning amino acids 57-64 is critical for interaction with the extracellular Toll-like receptor 2 domain. Biochem Biophys Res Commun. 2005 Mar 4,328(1):173-6. * Sing A et al. Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression. J Exp Med. 2002 Oct 21,196(8):1017-24. * Stöckl J et al. Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL. J Immunol. 2001 Sep 1,167(5):2724-33. *Funda DP et al. CD14 is expressed and released as soluble CD14 by human intestinal epithelial cells in vitro: lipopolysaccharide activation of epithelial cells revisited. Infect Immun. 2001 Jun,69(6):3772-81. * Bazil V et al. Structural relationship between the soluble and membrane-bound forms of human monocyte surface glycoprotein CD14. Mol Immunol. 1989 Jul;26(7):657-62. |
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