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MHC Class II antibody (M5/114)
I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek
As low as
$311.50
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00113204
MHC Class II antibody (M5/114)
| ID Covalab | mab20032 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | M5/114 |
| Isotype | IgG2b |
| Raised in | Rat |
| Immunogen | Activated C57BL/6 mouse spleen cells |
| Activity cross reaction | Reacts with mouse MHC class II glycoproteins including I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but not with I-Af, I-Ak and I-As. |
| Species | Ms |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | None |
| Storage instructions | Store at 2-8°C. Do not freeze. |
| Target | MHC Class II |
| Applications | FA, FC, IHC, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: FC (2 μg/ml) FA (Blocking of T cell proliferative responses) |
| Publication | *Kuwano Y et al. CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells. Int Immunol. 2007 Aug,19(8):977-92. *Zang W et al. MHC Class II-mediated apoptosis by a nonpolymorphic MHC Class II peptide proceeds by activation of protein kinase C. J Am Soc Nephrol. 2005 Dec,16(12):3661-8. *Beers C et al. Cathepsin S controls MHC class II-mediated antigen presentation by epithelial cells in vivo. J Immunol. 2005 Feb 1,174(3):1205-12. *Kleijmeer M et al. Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. J Cell Biol. 2001 Oct 1,155(1):53-63. |
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