CRMP-2 pY479 antibody

Dihydropyrimidinase-related protein 2 (DRP-2)
N2A3
Unc-33-like phosphoprotein 2 (ULIP-2)
Gene name : DPYSL2, CRMP2, ULIP2
As low as $235.00
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00102106
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
More Information
ID Covalab pab0479-IP
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide derived from C-terminal domain containing phospho-tyrosine 479 (pY479) of human CRMP-2
Activity cross reaction Reacts with CRMP-2 pY479 from human, rat and mouse. No cross reactivity was detected with CRMP1, CRMP3, CRMP4 or CRMP5
Species Hu, Ms, Rat
Labelling None
Form Antigen affinity purified
Preservative NaN3 0.02%
Storage instructions Store at -20°C
Antibodies are guaranteed for 6 month from date of receipt.
Target Collapsin response mediator protein 2 (CRMP-2)
Uniprot ID Q16555
Applications ELISA, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/200
- WB : 1/100 to 1/1 000
Publication Varrin-Doyer M et al. Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. J Biol Chem. 2009 May 8:284(19):13265-76.
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