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PAR4 antibody
PRKC apoptosis WT1 regulator protein
Prostate apoptosis response 4 protein, Par-4
Gene name: PAWR, PAR4
Prostate apoptosis response 4 protein, Par-4
Gene name: PAWR, PAR4
As low as
$528.40
In stock
Ref
00101563
The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms' tumor. Par-4 (for prostate apoptosis response) is a WT1-interacting protein that also functions as a transcriptional repressor. Par-4 contains a putative leucine zipper domain and is specifically upregulated during apoptosis of prostate cells.
| ID Covalab | pab52115 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptides corresponding to the N-terminal sequence (MATGGYRTSSGLGGS) and C-terminal sequence (QENKTLLKVVGQLTR) of human PAR4. |
| Activity cross reaction | Reacts with human PAR4. |
| Species | Hu |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | PAR4 |
| Applications | WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (1:500 - 1:1000) |
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