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Beclin-1 antibody (4H10)
Beclin-1
Coiled-coil myosin-like BCL2-interacting protein
Protein GT197, Beclin 1, beclin1
Gene name: BECN1, ATG6, GT197, VPS30
Coiled-coil myosin-like BCL2-interacting protein
Protein GT197, Beclin 1, beclin1
Gene name: BECN1, ATG6, GT197, VPS30
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00098966
Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus
| ID Covalab | mab50763 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | 4H10 |
| Isotype | IgG1 / Kappa |
| Raised in | Mouse |
| Immunogen | Full length human Beclin 1 protein |
| Activity cross reaction | Reacts with human ~52 kDa Beclin 1 protein. May cross-react with protein from monkey (99%),mouse and bovine (98%), porcine, rat and horse (97% ) and chicken (91% sequence homology) . |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein G) |
| Preservative | NaN3 0.05% |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Beclin-1 |
| Uniprot ID | Q14457 |
| Gene ID | 8678 |
| Applications | IHC - P, IP, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: WB (2 µg/ml) IHC - P (1:50 - 1:100) |
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