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CD209 / DC-SIGN (Internal) antibody
CD209 antigen
C-type lectin domain family 4 member L
Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CDSIGN
Gene name: CD209, CLEC4L
C-type lectin domain family 4 member L
Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CDSIGN
Gene name: CD209, CLEC4L
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00016327
Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.
| ID Covalab | pab70593 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide from human CD209 / DC-SIGN. |
| Activity cross reaction | Reacts with the center of human DC-DIGN |
| Species | Hu |
| Labelling | None |
| Form | Antigen affinity purified |
| Preservative | NaN3 0.02% |
| Storage instructions | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Target | CD209 / DC-SIGN |
| Uniprot ID | Q9NNX6 |
| Gene ID | 30835 |
| Applications | IHC - P, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC-P (5 µg/ml), WB (1 - 2 µg/ml) |
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