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Glucose-6-Phosphate Isomerase (GPI) pS185 antibody
Autocrine motility factor (AMF)
Neuroleukin (NLK)
Phosphoglucose isomerase (PGI)
Phosphohexose isomerase (PHI)
Sperm antigen 36 (SA-36)
Gene name: GPI
Neuroleukin (NLK)
Phosphoglucose isomerase (PGI)
Phosphohexose isomerase (PHI)
Sperm antigen 36 (SA-36)
Gene name: GPI
As low as
$306.10
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00014382
Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.
| ID Covalab | pab0627 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from human GPI containing a phosphoserine at position 185 |
| Activity cross reaction | Reacts with human 65 kDa GPI protein with a phosphoserine at position 185. Do not cross react with non-phospho GPI protein. |
| Species | Hu |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Glucose-6-Phosphate Isomerase (GPI) pS185 |
| Uniprot ID | P06744 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - IHC : 1/200 to 1/1 000 - WB : 1/500 to 1/5 000 |
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