Transcription factor E2F1 acetyl-lysine 120 and 125 (E2F-1) antibody

PBR3
PRB-binding protein E2F-1
Retinoblastoma-associated protein 1 (RBAP-1)
Retinoblastoma-binding protein 3 (RBBP-3)
Gene name: E2F1, RBBP3
As low as $306.10
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00013938
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
More Information
ID Covalab pab0726
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide derived from internal domain of human E2F-1 protein containing acetyl lysine 120 and 125
Activity cross reaction Reacts with human E2F-1 acK120 and acK125. May cross-react with E2F-1 from mouse and other species due to sequence homology
Species Hu, Ms
Labelling None
Form Antiserum
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Transcription factor E2F1 acetyl-lysine 120 and 125 (E2F-1)
Uniprot ID Q01094
Applications ELISA, IHC, WB
Working dilutions Optimal dilutions should be determined by the end user.
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