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Glutamate [NMDA] receptor subunit zeta-1 precursor (NMD-R1) antibody
Glutamate [NMDA] receptor subunit zeta-1
N-methyl-D-aspartate receptor subunit NR1 (NMD-R1)
Gene Name : GRIN1, NMDAR1
N-methyl-D-aspartate receptor subunit NR1 (NMD-R1)
Gene Name : GRIN1, NMDAR1
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00013742
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
| ID Covalab | pab0759-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from Cter domain of human NMD-R1 protein |
| Activity cross reaction | Reacts with human NMD-R1 protein isoforma 4, 6 and 7 . May cross react with mouse, rat and dog due to sequence homology. Do not react with isoforms 1, 2, 3 and 5 of human NMD-R1. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Glutamate [NMDA] receptor subunit zeta-1 |
| Uniprot ID | Q05586 |
| Gene ID | 2902 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: WB: 1/200-1/1000 IHC: 1/50-1/200 |
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