Forkhead box protein O (dFOXO) antibody

Forkhead box protein O, dFOXO,Protein FKHR
Gene name: foxo, Afx
As low as $306.10
In stock
Ref
00013710
Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.
More Information
ID Covalab pab0768
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide derived from Nter domain of the Drosophila dFOXO protein.
Activity cross reaction Reacts with the Drosophila melanogaster dFOXO protein
Species D. mel.
Labelling None
Form Antiserum
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Forkhead box protein O
Uniprot ID Q95V55
Gene ID 41709
Applications ELISA, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
WB (1:500 - 1:2000)
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