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Cartilage oligomeric matrix protein antibody
Thrombospondin-5 (TSP5)
Gene name: COMP
Gene name: COMP
As low as
$323.40
In stock
Ref
00013085
Play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Play a role in the pathogenesis of osteoarthritis. Suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP).
| ID Covalab | pab0027-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | A 16 residue synthetic peptide derived from specific domain of Complexe Oligomatrix Protein |
| Activity cross reaction | Reacts with human COMP from cartilage matrix. |
| Species | Hu |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Cartilage oligomeric matrix protein (COMP) |
| Uniprot ID | P49747 |
| Applications | ELISA, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : IHC 1:200 - 1:1000 WB 1:200 - 1:1000 |
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